Could an ultrasound replace MRI for heart monitoring?

NCT ID NCT05186415

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether using a contrast dye during 3D ultrasound can accurately measure the size and function of the right heart chamber in people who had surgery for congenital heart disease. 25 participants received an injection of Lumason (an ultrasound contrast agent) and then had a 3D echocardiogram. The results were compared to standard cardiac MRI measurements to see if the ultrasound method is reliable enough for routine use.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Sulfur hexafluoride lipid microspheres (Lumason)

What this could lead to

If successful, this could provide a faster, cheaper, and safer way to monitor heart function in people with repaired congenital heart disease, reducing the need for frequent MRIs.

What could go wrong

This is a small, early-phase study with only 25 participants, so results may not apply to everyone. The contrast agent also carries a small risk of allergic reactions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pulmonary valve insufficiency respiratory failure tetralogy of fallot

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Nemours Childrens Hospital

    Wilmington, Delaware, 19803, United States