Could an ultrasound replace MRI for heart monitoring?
NCT ID NCT05186415
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether using a contrast dye during 3D ultrasound can accurately measure the size and function of the right heart chamber in people who had surgery for congenital heart disease. 25 participants received an injection of Lumason (an ultrasound contrast agent) and then had a 3D echocardiogram. The results were compared to standard cardiac MRI measurements to see if the ultrasound method is reliable enough for routine use.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Sulfur hexafluoride lipid microspheres (Lumason)
- What this could lead to
- If successful, this could provide a faster, cheaper, and safer way to monitor heart function in people with repaired congenital heart disease, reducing the need for frequent MRIs.
- What could go wrong
- This is a small, early-phase study with only 25 participants, so results may not apply to everyone. The contrast agent also carries a small risk of allergic reactions.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Nemours Childrens Hospital
Wilmington, Delaware, 19803, United States
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