Personalized brain maps could make Parkinson's stimulation more precise

NCT ID NCT06618157

ENROLLING_BY_INVITATION Symptom relief Sponsor: Duke University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether using advanced brain imaging to guide deep brain stimulation (DBS) can better control tremor in people with Parkinson's disease while avoiding side effects like involuntary movements. Twenty adults who already have DBS implants will have their stimulation settings optimized based on individual brain pathways. The goal is to see if this personalized approach improves tremor control compared to standard care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: deep brain stimulation (DBS) device
What this could lead to: If it works, this could lead to more precise DBS settings that better control tremor and avoid worsening involuntary movements in Parkinson's patients.
What could go wrong: This is a small, early-stage study with only 20 participants, so results may not apply to everyone. The approach is still experimental and may not improve symptoms for all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Dyskinesias Parkinson disease Tremor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DYSKINESIAS PARKINSON DISEASE TREMOR

Contacts and locations

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Locations

Duke Health Center at Morreene Road

Durham, North Carolina, 27705, United States

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