Which Tear-Duct surgery works better? a Head-to-Head test
NCT ID NCT07754058
First seen Aug 10, 2026 · Last updated Aug 11, 2026 · Updated 1 time
Summary
This trial compares two operations for primary acquired nasolacrimal duct obstruction, a condition where tears cannot drain normally from the eye into the nose, causing persistent tearing. One surgery uses a small skin incision near the inner corner of the eye, while the other goes through the nose with an endoscope and powered tools. Both procedures apply mitomycin C during surgery to reduce scarring. The study follows 60 participants for 12 months to see which approach keeps the new tear drainage opening clear and better relieves tearing symptoms.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Two surgical procedures: external dacryocystorhinostomy (through a skin incision near the inner eye) and powered endoscopic dacryocystorhinostomy (through the nose with an endoscope), both with mitomycin C applied during surgery to reduce scarring.
- What this could lead to
- If one approach proves better, it could point to a preferred surgical method for restoring tear drainage and reducing tearing in people with blocked tear ducts.
- What could go wrong
- This is a single trial with 60 participants, so results may not apply to everyone. Surgery carries risks like infection, bleeding, or scarring, and the new opening may close over time.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Military Institute of Medicine - National Research Institute
Warsaw, Masovian Voivodeship, 04-141, Poland
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Other studies related to the condition(s) this trial covers.