Which mesh works best for prolapse? new study compares two options

NCT ID NCT03681223

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two different surgical meshes used to repair vaginal vault prolapse, a condition where the top of the vagina drops down. About 100 women having laparoscopic or robotic surgery received either Restorelle® Y mesh or Vertessa® Lite Y mesh. The goal was to see if the newer mesh works just as well as the standard one in preventing prolapse from coming back.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

surgical mesh (Restorelle® Y mesh or Vertessa® Lite Y mesh)

What this could lead to

If successful, this could show that Vertessa® Lite Y mesh is a safe and effective alternative to Restorelle® Y mesh for prolapse repair, giving surgeons more options.

What could go wrong

This is a small, completed trial with 106 participants, so results may not apply to everyone. Both meshes are already used in practice, so this is a comparison, not a breakthrough.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pelvic organ prolapse pelvic organ prolapse, susceptibility to

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States