New balloon and laser combo may save legs and money

NCT ID NCT02599389

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested three ways to treat leg arteries that have reblocked after stent placement: standard balloon angioplasty, a drug-coated balloon, and a laser plus drug-coated balloon. The goal was to see which approach is most cost-effective over 18 months. The trial involved 222 adults with symptoms like leg pain or poor circulation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

drug-coated balloon (paclitaxel) and excimer laser

What this could lead to

If successful, this could identify a more cost-effective way to treat reblocked stents in leg arteries, potentially improving blood flow and reducing the need for repeat procedures.

What could go wrong

This is a completed phase 3 trial, but the results may not apply to all patients. The treatments carry risks like vessel damage or recurrence of blockage, and the cost benefits may vary.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre Hospitalier Universitaire de Besançon

    Besançon, 25030, France

  • Centre Hospitalier Universitaire de Clermont-Ferrand

    Clermont-Ferrand, 63000, France

  • Centre Hospitalier Universitaire de Dijon

    Dijon, 21079, France

  • Centre Hospitalier Universitaire de Nantes

    Nantes, 44093, France

  • Centre Hospitalier Universitaire de St Etienne

    Saint-Etienne, 42055, France

  • Centre Hospitalier Universitaire de Strasbourg

    Strasbourg, 67091, France

  • Clinique Pasteur

    Toulouse, 31076, France

  • Clinique Rhône Durance

    Avignon, 84000, France

  • Clinique de L'Europe

    Rouen, 76100, France

  • Hospices Civils de Lyon

    Lyon, 69000, France

  • Hôpital Européen Georges Pompidou - AP-HP de Paris

    Paris, 75015, France

  • Polyclinique Les Fleurs

    Ollioules, 83190, France

  • University Hospital of Bordeaux - Hospital Pellegrin

    Bordeaux, 33000, France