Scientists test synthetic nicotine: is it safer or just different?

NCT ID NCT05962229

First seen Jan 11, 2026 · Last updated May 20, 2026 · Updated 20 times

Summary

This study looks at how the body handles synthetic nicotine compared to natural nicotine from tobacco. About 18 experienced e-cigarette users will try three types of nicotine liquid and have their blood, heart rate, and cravings measured. The goal is to understand if synthetic nicotine acts differently in the body, which could help inform future regulations or products.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Zuckerberg San Francisco General Hospital (ZSFG)

    RECRUITING

    San Francisco, California, 94110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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