New sperm prep device could boost IVF success

NCT ID NCT06990841

Recruiting now Knowledge-focused Sponsor: Richard Kordus, PhD, HCLD (ABB) Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study compares a new sperm separation device (LensHooke CA0) with the standard gradient/swim-up method to see which reduces DNA damage in sperm. Each semen sample is split, and half the partner's eggs are fertilized with sperm from each method. Researchers will check DNA fragmentation, sperm quality, embryo development, and pregnancy rates in 50 couples.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: sperm separation device (LensHooke CA0)
What this could lead to: If one method clearly reduces DNA damage, it could lead to better embryo quality and higher pregnancy rates in IVF.
What could go wrong: This is a small, early-stage study (50 participants) comparing two lab techniques, not a treatment. Results may not apply to all fertility cases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DNA DAMAGE DNA STRAND BREAKS SPERM DNA FRAGMENTATION

Contacts and locations

Locations

Prisma Health-Upstate Fertility Center of the Caroliinas
RECRUITING

Greenville, South Carolina, 29605, United States

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