Which COVID-19 booster works better? new study pits novavax against pfizer

NCT ID NCT06065176

First seen Nov 21, 2025 · Last updated May 01, 2026 · Updated 19 times

Summary

This study tested how well two updated COVID-19 vaccines (Novavax and Pfizer mRNA) protect adults from getting sick. About 1,188 people who had already received at least two mRNA vaccine doses took part. Participants were randomly assigned to get either the Novavax or Pfizer vaccine, or no updated vaccine, and were monitored for 20 weeks with weekly tests and surveys. The goal was to see which vaccine offers better protection against symptomatic COVID-19.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Utah School of Medicine

    Salt Lake City, Utah, 84108, United States

Conditions

Explore the condition pages connected to this study.