Which iron pill is kinder to blood donors?

NCT ID NCT05678647

Completed Symptom relief Sponsor: Uppsala University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two different oral iron supplements given to regular blood donors after donation. One is a newer form called sucrosomial iron (SiderAl Forte) and the other is standard iron sulfate (Duroferon). The goal was to see which one causes fewer side effects and whether it helps with restless legs symptoms. 120 donors participated, and the results will help guide which supplement is better tolerated.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: sucrosomial iron (SiderAl Forte) and iron sulfate (Duroferon)
What this could lead to: If one supplement causes fewer side effects, it could become the preferred option for blood donors needing iron replacement.
What could go wrong: This is a small, completed trial with only 120 participants, so results may not apply to all donors. Side effects are still possible with either supplement.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BLOOD DONATION

Contacts and locations

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Locations

Clinical Immunology and Transfusion Medicine, Uppsala University Hospital

Uppsala, 75237, Sweden

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