Heart failure emergency: which drug works best first?

NCT ID NCT05276219

First seen Apr 28, 2026 · Last updated May 24, 2026 · Updated 6 times

Summary

This study tests whether a drug that widens blood vessels (nitrates) works better than a standard water pill (furosemide), or if using both together is best, for people with sudden fluid buildup in the lungs from heart failure. About 1,100 adults with severe shortness of breath and low oxygen levels will be randomly assigned to one of three treatments in the emergency room. The goal is to see which approach keeps people alive and out of the hospital for more days over the next month.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bispebjerg Hospital

    RECRUITING

    Copenhagen, Copenhagen, 2000, Denmark

    Contact

    Contact Email: •••••@•••••

  • Hvidovre Hospital

    RECRUITING

    Copenhagen, Copenhagen, 2650, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Nordsjællands Hospital

    RECRUITING

    Hillerød, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Roskilde Hospital

    NOT_YET_RECRUITING

    Roskilde, Denmark

    Contact Email: •••••@•••••

    Contact

Conditions

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