Battle of the scopes: which endoscopic technique removes rectal tumors best?

NCT ID NCT07612748

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks back at 483 patients who had small rectal neuroendocrine tumors (less than 2 cm) removed using one of two endoscopic techniques: endoscopic submucosal dissection (ESD) or endoscopic partial muscle resection (EPMR). The goal is to compare how often each method leaves cancer cells at the edge of the removed tissue (positive margin), along with other outcomes like procedure time and complications. The findings may help doctors choose the safer, more effective approach for these tumors.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors choose the best endoscopic technique for removing small rectal neuroendocrine tumors, potentially reducing the chance of leftover cancer.
What could go wrong
This is a retrospective review, not a controlled trial, so results may be influenced by patient selection. The findings may not apply to larger or more advanced tumors.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • the First Hospital of Jilin University

    RECRUITING

    Changchun, Jilin, 130021, China

  • the First Hospital of Jilin University

    ACTIVE_NOT_RECRUITING

    Changchun, 130021, China

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