Which pill works better for chronic pain? new study pits two antidepressants Head-to-Head

NCT ID NCT03548454

First seen Nov 06, 2025 · Last updated May 24, 2026 · Updated 26 times

Summary

This study compared two antidepressant medications, duloxetine and desipramine, to see which one works better for reducing chronic pain. About 86 adults with pain lasting more than 3 months took one of the two drugs for 6 months. Researchers measured pain levels and physical function to find out which treatment helped more.

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Contacts and locations

Locations

  • Stanford Pain Management Center

    Redwood City, California, 94063, United States

Conditions

Explore the condition pages connected to this study.