New trial tests if adding a blood thinner to standard care prevents heart attacks in rare artery condition

NCT ID NCT07511257

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two blood-thinning approaches in 326 adults with acute coronary syndrome and coronary artery ectasia (enlarged heart arteries). One group gets standard dual antiplatelet therapy (aspirin plus clopidogrel), while the other gets clopidogrel plus the anticoagulant rivaroxaban. The goal is to see if adding rivaroxaban reduces major heart events without causing too much bleeding.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

aspirin, clopidogrel, and rivaroxaban

What this could lead to

If successful, this could establish a better blood-thinning strategy to prevent heart attacks and repeat procedures in people with both acute coronary syndrome and coronary artery ectasia.

What could go wrong

This is a phase 4 trial, but the condition is uncommon, so results may not apply broadly. Adding anticoagulation also raises the risk of bleeding, which could outweigh the benefits.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute coronary syndrome acute myocardial infarction coronary aneurysm myocardial infarction ST-elevation myocardial infarction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Instituto Nacional de Cardiologia "Ignacio Chávez"

    RECRUITING

    Mexico City, Tlalpan, 14080, Mexico

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact