Spine surgery Wake-Up race: which drug wins?
NCT ID NCT07443163
First seen Mar 14, 2026 · Last updated Jun 22, 2026 · Updated 17 times
Summary
This study compares two drugs, magnesium sulfate and dexmedetomidine, used alongside total intravenous anesthesia during lumbar spine surgery. The goal is to see which drug helps patients wake up and have their breathing tube removed faster. Forty adults scheduled for spine surgery will take part, and the study is double-blinded, meaning neither patients nor doctors know who gets which drug.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
magnesium sulfate and dexmedetomidine
What this could lead to
If this trial succeeds, it could show that one of these drugs helps patients wake up faster and need less pain medicine after spine surgery.
What could go wrong
This is a small early-stage trial with only 40 people, so results may not apply to everyone. The drugs may not differ much in their effects.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.