Double PET scan may unlock secrets of gut tumors

NCT ID NCT04804371

Ongoing Knowledge-focused Sponsor: University Health Network, Toronto Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study is testing whether combining two different PET scans can give doctors a clearer picture of neuroendocrine tumors (NETs) in the gut. The scans measure how tumors take up different tracers, which may reveal whether a tumor is slow-growing or aggressive. The goal is to see if this information helps doctors choose the best treatment for each patient. The study involves 40 adults with well-differentiated G2-G3 GEP-NETs.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: F18-FDG (a radioactive tracer for PET scans)
What this could lead to: If successful, this could help doctors choose better treatments for patients with intermediate-grade neuroendocrine tumors by identifying which tumors are more aggressive.
What could go wrong: This is a small pilot study with only 40 participants, so results may not apply to everyone. It is designed to gather information, not to test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

digestive system neuroendocrine tumor, grade 1/2 neuroendocrine neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NEUROENDOCRINE TUMORS

Contacts and locations

Locations

Princess Margaret Cancer Centre

Toronto, Ontario, M5G 2M9, Canada

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