New drug combo aims to tame tough rheumatoid arthritis
NCT ID NCT05306353
First seen Feb 01, 2026 · Last updated May 09, 2026 · Updated 17 times
Summary
This study tested whether adding a 12-week course of VIB4920 to standard TNF-inhibitor therapy could improve disease control in people with rheumatoid arthritis who did not respond well to TNF-inhibitors alone. Only 2 participants were enrolled before the study was stopped. The goal was to reduce joint swelling and pain, but results are limited due to early termination.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Brigham & Women's Hospital: Department of Medicine, Rheumatology, Immunology
Boston, Massachusetts, 02215, United States
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Duke University Medical Center: Division of Rheumatology and Immunology
Durham, North Carolina, 27710, United States
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University of California San Francisco School of Medicine: Lupus Clinic and Rheumatology Clinical Research Center
San Francisco, California, 94110, United States
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University of Colorado School of Medicine: Division of Rheumatology
Aurora, Colorado, 80045, United States
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University of Michigan Health System: Department of Internal Medicine, Division of Rheumatology
Ann Arbor, Michigan, 48109, United States
Conditions
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