New drug combo fails to advance in resistant breast cancer trial

NCT ID NCT01589861

First seen Apr 25, 2026 · Last updated Apr 28, 2026 · Updated 1 time

Summary

This study tested a combination of two oral drugs, BKM120 and lapatinib, in people with a specific type of advanced breast cancer (HER2-positive) that had stopped responding to the standard drug trastuzumab. The goal was to see if the combination was safe and could shrink tumors. The study was terminated early, so results are limited.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BREAST CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Institut Paoli-Calmettes

    Marseille, 13008, France

Conditions

Explore the condition pages connected to this study.