New drug combo shows promise in Hard-to-Treat cancers
NCT ID NCT03156114
First seen Feb 01, 2026 · Last updated May 13, 2026 · Updated 7 times
Summary
This study tested two experimental drugs, BI 754111 and BI 754091, that help the immune system attack cancer. It included 172 adults with advanced solid tumors, including non-small cell lung cancer that had returned after prior treatment. The first part found the safest dose, and the second part checked if the combination could shrink tumors. Treatment was given every 3 weeks for up to one year.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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BioVirtus Research Site Sp. z o.o.
Józefów, 05-410, Poland
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Cross Cancer Institute (University of Alberta)
Edmonton, Alberta, T6G 1Z2, Canada
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Florida Cancer Specialists
Sarasota, Florida, 34232, United States
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Froedtert and The Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Hospital General Universitario Gregorio Marañón
Madrid, 28007, Spain
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Hospital Politècnic La Fe
Valencia, 46026, Spain
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Hospital Universitari Dexeus
Barcelona, 08028, Spain
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Hospital Universitario HM Sanchinarro
Madrid, 28050, Spain
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John Theurer Cancer Center
Hackensack, New Jersey, 07601, United States
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Oncology Center-Maria Sklodowska-Curie Institute
Warsaw, 02-781, Poland
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Princess Margaret Cancer Centre
Toronto, Ontario, M5G 1Z9, Canada
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Sarah Cannon Research Institute
London, W1G 6AD, United Kingdom
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Stephenson Cancer Center
Oklahoma City, Oklahoma, 73104, United States
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Tennessee Oncology, PLLC
Nashville, Tennessee, 37203, United States
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University of Miami
Miami, Florida, 33136, United States
Conditions
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