New antibody COM701 aims to keep ovarian cancer at bay
NCT ID NCT06888921
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This clinical trial tests whether the experimental antibody COM701 can delay the return of ovarian cancer in people whose cancer has come back but still responds to platinum chemotherapy. About 60 participants will receive COM701 or a placebo every three weeks as maintenance therapy. The study will measure how long the cancer stays under control and monitor for side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
COM701 (an experimental antibody)
What this could lead to
If it works, this could provide a new maintenance option to delay ovarian cancer recurrence after chemotherapy.
What could go wrong
This is an early Phase 1/2 trial with only 60 participants, so results may not apply broadly. Side effects are still being studied, and the drug may not slow cancer progression.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for OVARIAN CANCER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Assuta Medical Center
RECRUITINGAshdod, 7747629, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Avera Cancer Institute
RECRUITINGSioux Falls, South Dakota, 57105, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Centre Eugene Marquis
RECRUITINGRennes, 35042, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Centre Hospitalier Regional et Universitaire de Besancon - Hopital Jean-Minjoz
RECRUITINGBesançon, France, 25000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Centre Oscar Lambret
RECRUITINGLille, 59000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Corewell Health
RECRUITINGGrand Rapids, Michigan, 49503, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Georgia Cancer Center at Augusta University
RECRUITINGAugusta, Georgia, 30912, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Gustave Roussy
RECRUITINGVillejuif, 94800, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Hadassah, University Hospital Ein Kerem
RECRUITINGJerusalem, 9112001, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Hospices Civils de Lyon- Centre Hospitalier Lyon Sud
RECRUITINGPierre-Bénite, 69310, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Institut Paoli-Calmettes
RECRUITINGMarseille, 13009, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Institut de Cancerologie de l'Ouest- Site Rene Gauducheau
RECRUITINGSaint-Herblain, 44805, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Levine Cancer Institute
RECRUITINGCharlotte, North Carolina, 28204, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Memorial Sloan Kettering Cancer Center- Main Campus
RECRUITINGNew York, New York, 10065, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Northwestern Memorial Hospital
RECRUITINGWarrenville, Illinois, 60555, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
OU Health Stephenson Cancer Center
RECRUITINGOklahoma City, Oklahoma, 73104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Ohio State University Wexner Medical Center Gynecologic Oncology at Mill Run
RECRUITINGHilliard, Ohio, 43026, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Oncopole Claudius Regaud
RECRUITINGToulouse, France, 31059, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Rambam Health Care Campus
RECRUITINGHaifa, 3109601, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Shaare Zedek Medical Center
RECRUITINGJerusalem, 9103102, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
The Chaim Sheba Medical Center
RECRUITINGRamat Gan, 5265601, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
The Edith Wolfson Medical Center
RECRUITINGHolon, 5822012, Israel
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
The University of Chicago Medical Center
RECRUITINGChicago, Illinois, 60637, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
UPMC Magee- Womens Hospital
RECRUITINGPittsburgh, Pennsylvania, 15213, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
UVA Comprehensive Cancer Center
RECRUITINGCharlottesville, Virginia, 22903, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
University of Rochester Medical Center
RECRUITINGRochester, New York, 14642, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
West Cancer Center
WITHDRAWNGermantown, Tennessee, 38138, United States