New filler study aims to see if COLD-X™ technology keeps wrinkles away longer

NCT ID NCT07255261

Recruiting now Symptom relief Sponsor: Symatese Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 460 adults who choose to get hyaluronic acid-based dermal fillers for their lips, cheeks, or wrinkles around the mouth and eyes. Researchers will check every 6 months for up to 2 years to see how long the effects last and whether any side effects occur. Participants can get a repeat treatment at 12 or 18 months if the area returns to its original state.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: hyaluronic acid-based dermal fillers (COLD-X™ technology)
What this could lead to: If successful, this study could confirm that these fillers provide lasting aesthetic improvement for up to 24 months with a good safety profile.
What could go wrong: This is a post-market observational study, not a controlled trial, so results may not prove superiority over other fillers. Side effects like swelling or bruising are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHEEK AUGMENTATION INFRAORBITAL HOLLOWS LIPS ENHANCEMENT NASOLABIAL FOLD WRINKLES PERIORAL WRINKLES

Contacts and locations

Locations

Aesthé - Marais.
RECRUITING

Paris, 75004, France
Cabinet médical
RECRUITING

Lyon, 69005, France
Cabinet médical
RECRUITING

Paris, 75008, France
Cabinet médical
RECRUITING

Paris, 75116, France
Cabinet médical
RECRUITING

Saint-Maur-des-Fossés, 94100, France
Centre Laser Palaiseau
RECRUITING

Palaiseau, 91120, France
Centre Médical Saint Jean
RECRUITING

Arras, 62000, France
Palais de Flore
RECRUITING

Lyon, 69006, France

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