Old drug, new target: can a common Anti-Inflammatory pill protect diabetic hearts?

This study is testing if adding a low daily dose of colchicine, an existing anti-inflammatory drug, to standard diabetes care can reduce inflammation and lower the risk of heart disease in people with long-standing Type 1 diabetes. About 100 participants, who already have or are at high risk for heart disease, will take either colchicine or a placebo pill daily for 6 to 12 months. Researchers will track markers of inflammation, blood sugar control, and heart health during treatment and for 5 years afterward.