Can a brain ZAP boost thinking skills in severe mental illness?
NCT ID NCT06378463
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether combining cognitive remediation training (a computer-based program to improve thinking skills) with mild brain stimulation (transcranial direct current stimulation) can help people with severe mental illness who live in supported housing. The goal is to improve daily functioning and personal recovery. 126 adults aged 18-65 are taking part, and the study compares the active treatment to a sham (fake) stimulation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
transcranial direct current stimulation (tDCS)
What this could lead to
If successful, this could point toward a way to improve thinking and daily living skills for people with severe mental illness who need supported housing.
What could go wrong
This is an early-stage study with only 126 participants, so results may not apply widely. The brain stimulation is mild, but individual responses can vary and benefits may be small.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Cosis
Assen, Drenthe, 9400 AE, Netherlands
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GGZ Friesland
Leeuwarden, Provincie Friesland, 8932 PA, Netherlands
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Lentis
Zuidlaren, Drenthe, 9470 AC, Netherlands