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Brain training may help prevent alcohol relapse after withdrawal

NCT ID NCT07690423

Disease control Sponsor: Centre Hospitalier Esquirol Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 08, 2026 · Last updated Jul 10, 2026 · Updated 2 times

Summary

This trial investigates whether cognitive cycling—a series of structured mental exercises—can help prevent relapse in adults with alcohol use disorder after they complete alcohol withdrawal. Participants are randomly assigned to receive either 12 cognitive cycling sessions over four weeks plus standard care, or standard care with 12 scheduled phone interviews. The study tracks abstinence rates at one and three months after hospital discharge, along with changes in cravings, cognitive function, and mood.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
cognitive cycling sessions
What this could lead to
If effective, this approach could offer a non-drug method to help people with alcohol use disorder maintain abstinence after withdrawal.
What could go wrong
This is a small, early-stage trial with 128 participants, so results may not apply broadly. The intervention is time-intensive and may not outperform standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 128 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * adults aged ≥ 18 years * patients with a diagnosis of alcohol use disorder (AUD) according to DSM-5 criteria * who have been hospitalized for complex withdrawal and aim to maintain abstinence after discharge * patients must have preserved cognitive function, defined as a Montreal Cognitive Assessment (MoCA) score ≥ 26 * patients must provide written informed consent Exclusion Criteria: * pregnant women * patients with unstable psychiatric or somatic conditions * with a contraindication to physical activity * participants in structured rehabilitation programs during the first month * adult under guardianship * with inability to understand French or provide informed consent * with major neurocognitive disorder * with regular physical activity * participation in another interventional study interfering with outcomes

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Conditions

The condition(s) this trial relates to.

alcohol abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alcohol use disorder (AUD) Cognitive cycling Treatment

How to take part

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  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

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  2. A doctor treating you

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