New shot at recovery: study tests monthly injections to curb cocaine cravings

NCT ID NCT05262270

Summary

This study tested whether two long-acting, injectable medications—naltrexone and buprenorphine—could help people with cocaine use disorder reduce or stop their cocaine use. Over 400 adults participated in the 8-week trial, where half received the active medication injections and half received placebo (dummy) injections. The main goal was to see if the medication combination led to more cocaine-free urine tests compared to the placebo.

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Contacts and locations

Locations

  • Addictions Institute of Mount Sinai

    New York, New York, 10029, United States

  • Berman Center for Outcomes and Clinical Research at Hennepin Healthcare

    Minneapolis, Minnesota, 55404, United States

  • Center on Substance Use and Health (CSUH)

    San Francisco, California, 94102, United States

  • Cove Behavioral Health

    Tampa, Florida, 33605, United States

  • Mountain Manor Treatment Center

    Baltimore, Maryland, 21229, United States

  • UCLA Vine Street Clinic

    Los Angeles, California, 90038, United States

  • UTSW Medical Center, Center for Depression Research and Clinical Care

    Dallas, Texas, 75247, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35209, United States

  • University of Arkansas for Medical Sciences

    Little Rock, Arkansas, 72205, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • University of Illinois at Chicago

    Chicago, Illinois, 60608, United States

  • University of Texas Health San Antonio

    San Antonio, Texas, 78229, United States

Conditions

Explore the condition pages connected to this study.