CO2 levels may help kids need less anesthesia during surgery

NCT ID NCT06303518

Recruiting now Knowledge-focused Sponsor: University of British Columbia Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether changing the amount of carbon dioxide (CO2) in a child's breath during anesthesia affects how deeply asleep they are. Researchers will adjust CO2 levels in 100 children aged 3-11 and measure brain activity with a monitor. The goal is to see if higher CO2 can safely reduce the amount of anesthesia needed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: carbon dioxide (CO2) levels
What this could lead to: If it works, this could help anesthesiologists use less anesthesia medication in children, reducing side effects and costs.
What could go wrong: This is a small, early-phase study with only 100 children. It measures brain activity, not direct health outcomes, so benefits are uncertain.

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Conditions

The condition(s) this trial relates to.

Hypercapnia Hypocapnia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANESTHESIA HYPERCAPNIA HYPOCAPNIA

Contacts and locations

Locations

BC Children's Hospital
RECRUITING

Vancouver, British Columbia, V6H 3N1, Canada

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