New trial aims to stop CMV eye inflammation from returning

NCT ID NCT07513623

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether oral valganciclovir or ganciclovir eye drops can reduce the virus causing eye inflammation and prevent flare-ups. About 117 adults with CMV anterior uveitis will receive either antiviral treatment or placebo for 7 days, then some continue for 12 months. The goal is to find a better way to control the infection and keep the disease from coming back.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Valganciclovir (oral) and ganciclovir (eye drops)

What this could lead to

If successful, this could provide effective antiviral strategies to control CMV eye inflammation and reduce the risk of it coming back.

What could go wrong

This is an early phase 2 trial with a small number of participants. The treatments may not work better than placebo, and side effects from antiviral drugs are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anterior uveitis cytomegalovirus infection infectious anterior uveitis uveitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chang Gung University

    Taoyuan, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chiang Mai University

    Chiang Mai, Thailand

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chulalongkorn University

    Bangkok, Thailand

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Khon Kaen University

    Khon Kaen, Thailand

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Proctor Foundation, University of California San Francisco

    San Francisco, California, 94158, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stein Eye Institute, University of California Los Angeles

    Los Angeles, California, 90095, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••