Leukemia patients who failed stopping meds may get another shot at drug-free remission

NCT ID NCT06368414

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding asciminib to standard tyrosine kinase inhibitors (TKIs) can help people with chronic myeloid leukemia (CML) safely stop all medication and remain in remission. It includes 69 adults who have been on TKIs for at least 5 years but previously failed to stay in remission after stopping treatment. Participants will take asciminib plus their current TKI, then attempt to stop both and be monitored for one year.

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Conditions

The condition(s) this trial relates to.

chronic myelogenous leukemia, BCR-ABL1 positive Leukemia, Myeloid, Chronic-Phase

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Gachon University Gil Medical Center

    RECRUITING

    Incheon, Incheon, 21565, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••