Real-World check: Asciminib's performance in Tough-to-Treat CML

NCT ID NCT07640750

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study will follow about 98 adults with chronic myeloid leukemia who are taking asciminib after other treatments have stopped working. Researchers want to see how many patients achieve a major molecular response (a key sign of disease control) after two years. The goal is to understand how effective and tolerable asciminib is in real-world settings, outside of controlled clinical trials.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
asciminib
What this could lead to
If successful, this study could confirm that asciminib is a reliable option for controlling CML when other treatments have failed.
What could go wrong
This is an observational study, not a controlled trial, so results may be less definitive. It is also relatively small (98 participants) and not yet recruiting.

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Conditions

The condition(s) this trial relates to.

chronic myelogenous leukemia, BCR-ABL1 positive Leukemia, Myelogenous, Chronic, BCR-ABL Positive Leukemia, Myeloid, Chronic-Phase

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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Other studies related to the condition(s) this trial covers.