Stomach acid drug may change how schizophrenia medication works
NCT ID NCT07262736
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how a common stomach acid drug, pantoprazole, affects the levels of clozapine, a medication for schizophrenia. Thirty-three healthy volunteers took clozapine alone and again after several days of pantoprazole. Researchers measured drug concentrations in the blood to see if pantoprazole changes clozapine exposure, which could help personalize dosing in the future.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
clozapine and pantoprazole
What this could lead to
If successful, this study could help doctors adjust clozapine doses more safely when patients also take pantoprazole, reducing side effects or treatment failure.
What could go wrong
This is a small, early-phase trial in healthy volunteers, not patients. Results may not directly apply to people with schizophrenia or other medical conditions.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Pusat Sejahtera (Kesihatan & Pergigian)
Pulau Pinang, 11800, Malaysia