AI tool could unmask hidden cancers in blood clot patients

NCT ID NCT07310693

Recruiting now Knowledge-focused Sponsor: Infanta Leonor University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a computer model called the CLOVER score, which uses machine learning to predict whether a person with a blood clot might have an undiagnosed cancer. Researchers will check the model's accuracy in 500 patients over two years. If it works well, doctors could use it to decide who needs extra cancer screening.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could give doctors a reliable way to identify which blood-clot patients need cancer screening, potentially catching hidden cancers earlier.
What could go wrong: This is an observational validation study, not a treatment trial. The model may not perform as well in real-world settings, and it won't directly benefit participants.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer of unknown primary site venous thromboembolism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OCCULT CANCER VENOUS THROMBOEMBOLISM (VTE)

Contacts and locations

Locations

Hospital Clínic
RECRUITING

Barcelona, Barcelona, Spain
Hospital Clínico Universitario Virgen de la Arrixaca
RECRUITING

Murcia, Murcia, Spain
Hospital San Agustín
RECRUITING

Avilés, Principality of Asturias, Spain
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, Spain
Hospital Universitario Infanta Leonor
RECRUITING

Madrid, Madrid, 28051, Spain
Hospital Universitario La Paz
RECRUITING

Madrid, Madrid, 28051, Spain
Hospital Universitario Morales Meseguer
RECRUITING

Murcia, Murcia, Spain
Hospital Universitario Príncipe de Asturias
RECRUITING

Madrid, Madrid, 28051, Spain
Hospital Universitario Son Llatzer
RECRUITING

Balea, Spain
Hospital Universitario de Fuenlabrada
RECRUITING

Madrid, Spain
Hospital Universitario de Móstoles
RECRUITING

Madrid, Madrid, Spain
Hospital Universitatio del Sureste
RECRUITING

Madrid, Madrid, 28051, Spain

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