New device zaps brain in sync with tremors to quiet shaking hands

NCT ID NCT06993571

Recruiting now Symptom relief Sponsor: Universitätsklinikum Hamburg-Eppendorf Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a non-invasive device that delivers mild electrical stimulation to the cerebellum, timed precisely to each patient's hand tremor rhythm. Ten people with Parkinson's and moderate-to-severe hand tremor will receive both real and sham stimulation to see if the real treatment reduces shaking. The goal is to find a new, drug-free way to ease one of Parkinson's most stubborn symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: closed-loop transcranial alternating current stimulation (tACS) device
What this could lead to: If it works, this could point toward a drug-free, on-demand way to calm Parkinson's tremors without surgery or medication side effects.
What could go wrong: This is a very small, early feasibility study with only 10 people. The effect may be weak, temporary, or not work at all outside the lab.

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Conditions

The condition(s) this trial relates to.

Parkinson disease Tremor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSON'S DISEASE (PD) TREMOR

Contacts and locations

Locations

Universitätsklinikum Hamburg-Eppendorf
RECRUITING

Hamburg, Free and Hanseatic City of Hamburg, 20246, Germany

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