Two-Punch combo aims to wipe out leukemia, offering hope for treatment breaks

NCT ID NCT03708003

Summary

This trial tested a two-drug combination (ibrutinib and venetoclax) for adults with chronic lymphocytic leukemia (CLL) that had returned or stopped responding to prior treatment. The goal was to see if using the drugs together could achieve a deep remission, potentially allowing patients to take a break from continuous medication. The study enrolled 30 participants and was designed to carefully manage risks, starting with one drug before adding the second.

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Contacts and locations

Locations

  • IOSI - Ospedale San Giovanni

    Bellinzona, 6501, Switzerland

  • Inselspital

    Bern, 3010, Switzerland

  • Kantonsspital Aarau

    Aarau, CH-5001, Switzerland

  • Kantonsspital Graubünden

    Chur, 7000, Switzerland

  • Kantonsspital Liestal

    Liestal, CH-4410, Switzerland

  • Kantonsspital Münsterlingen

    Münsterlingen, 8596, Switzerland

  • Kantonsspital Winterthur

    Winterthur, 8401, Switzerland

  • Luzerner Kantonsspital

    Lucerne, 6000, Switzerland

  • Spital STS AG Thun

    Thun, 3600, Switzerland

  • Universitätsspital Basel

    Basel, 4031, Switzerland

  • Universitätsspital Zürich

    Zurich, 8091, Switzerland

Conditions

Explore the condition pages connected to this study.