New hope for CLL patients: targeted drug combos aim for deeper remission

NCT ID NCT05336812

First seen Feb 19, 2026 · Last updated May 15, 2026 · Updated 10 times

Summary

This study tests two drug combinations (acalabrutinib plus venetoclax or obinutuzumab) in people with untreated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma. The goal is to see if these combinations can shrink tumors and achieve very low levels of cancer cells in the bone marrow. About 52 adults will participate, receiving acalabrutinib first, then one of the two combos.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ohio State University Comprehensive Cancer Center

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.