New combo therapy aims to improve outcomes for older CLL patients

NCT ID NCT07321652

First seen Jan 09, 2026 · Last updated May 14, 2026 · Updated 11 times

Summary

This study compares a fixed-duration combination of two drugs (zanubrutinib and sonrotoclax) against continuous zanubrutinib alone in older adults with untreated chronic lymphocytic leukemia or small lymphocytic lymphoma. The goal is to see if the combination improves how long patients live without their cancer getting worse. About 466 participants will be enrolled, and the study is not yet recruiting.

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