Could stopping cancer drugs early be safer?

NCT ID NCT04722172

First seen Apr 11, 2026 · Last updated May 23, 2026 · Updated 8 times

Summary

This study tests if people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) can safely stop taking acalabrutinib and obinutuzumab once their cancer responds well, instead of continuing treatment indefinitely. The goal is to reduce side effects and prevent drug resistance. About 55 adults with untreated CLL or SLL will participate, and researchers will monitor how long they stay cancer-free after stopping treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hackensack Meridian Health (Data collection only)

    Hackensack, New Jersey, 07601, United States

  • Memorial Sloan Kettering Basking Ridge (All protocol activities)

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen (All protocol activities)

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Commack (All protocol activities)

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Monmouth (All protocol activities)

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau (All protocol activities)

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Westchester (All protocol activities)

    Harrison, New York, 10604, United States

Conditions

Explore the condition pages connected to this study.