New laser microscope could boost lung cancer detection during bronchoscopy

NCT ID NCT06079970

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares standard bronchoscopy (using a thin tube to look at the lungs) with and without an additional laser-based microscope called nCLE. The microscope helps doctors see if the sampling needle is in the right spot before taking tissue. About 208 adults with suspicious lung nodules will take part. The goal is to see if nCLE leads to more accurate diagnoses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

needle-based confocal laser endomicroscopy (nCLE) device

What this could lead to

If successful, this could make lung nodule diagnosis more accurate, reducing the need for repeat procedures or more invasive biopsies.

What could go wrong

This is a relatively small, early-stage trial (208 participants) comparing a new imaging technique to standard care. The improvement in diagnosis may be modest, and the device adds complexity and cost.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Amsterdam University Medical Centers

    RECRUITING

    Amsterdam, 1081 HV, Netherlands

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  • General University Hospital Prague

    RECRUITING

    Prague, Czechia

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  • Montefiore Medical Center

    RECRUITING

    New York, New York, 10467, United States

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  • Sotiria Hospital

    RECRUITING

    Athens, Greece

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  • Vienna General Hospital

    RECRUITING

    Vienna, Austria

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