New laser microscope could boost lung cancer detection during bronchoscopy

NCT ID NCT06079970

Recruiting now Diagnosis Sponsor: Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares standard bronchoscopy (using a thin tube to look at the lungs) with and without an additional laser-based microscope called nCLE. The microscope helps doctors see if the sampling needle is in the right spot before taking tissue. About 208 adults with suspicious lung nodules will take part. The goal is to see if nCLE leads to more accurate diagnoses.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: needle-based confocal laser endomicroscopy (nCLE) device
What this could lead to: If successful, this could make lung nodule diagnosis more accurate, reducing the need for repeat procedures or more invasive biopsies.
What could go wrong: This is a relatively small, early-stage trial (208 participants) comparing a new imaging technique to standard care. The improvement in diagnosis may be modest, and the device adds complexity and cost.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARCINOMA, NON-SMALL-CELL LUNG LUNG CANCER LUNG NEOPLASM MALIGNANT NEOPLASM OF LUNG

Contacts and locations

Locations

Amsterdam University Medical Centers
RECRUITING

Amsterdam, 1081 HV, Netherlands
General University Hospital Prague
RECRUITING

Prague, Czechia
Montefiore Medical Center
RECRUITING

New York, New York, 10467, United States
Sotiria Hospital
RECRUITING

Athens, Greece
Vienna General Hospital
RECRUITING

Vienna, Austria

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