New hope for halting MS disability: drug trial aims to save crucial arm function
NCT ID NCT04695080
Summary
This UK trial is testing whether a drug called cladribine can slow the loss of arm and hand function in people with advanced multiple sclerosis (MS). Over two years, about 200 participants will receive either the drug or a placebo to see which better protects their ability to perform daily tasks. The study also measures safety, quality of life, and brain changes to understand if this treatment can help control disease progression in advanced MS.
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Contacts and locations
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Locations
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Aneurin Bevan University Health Board
Newport, NP20 2UB, United Kingdom
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Anne Rowling Clinic, University of Edinburgh
Edinburgh, EH16 4SB, United Kingdom
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Cardiff University Hospital
Cardiff, CF14 4XW, United Kingdom
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Leeds Teaching Hospitals NHS Trust
Leeds, LS1 3EX, United Kingdom
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Lewisham and Greenwich NHS Trust
London, SE13 6LH, United Kingdom
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Luton and Dunstable Hospital
Luton, LU4 0DZ, United Kingdom
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Morriston Hospital, Swansea
Swansea, SA6 6NL, United Kingdom
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Nottingham University Hospital (Nottingham University Hospitals NHS Trust)
Nottingham, NG7 2UH, United Kingdom
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Queen Elizabeth University Hospital Glasgow
Glasgow, G51 4TF, United Kingdom
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Queen's Hospital (Havering and Redbridge University Hospitals NHS Trust)
London, RM7 0AG, United Kingdom
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Queens University Belfast (Belfast Health and Social Care Trust)
Belfast, BT12 6BA, United Kingdom
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Royal Free London NHS Foundation Trust
London, NW3 2QG, United Kingdom
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Royal London Hospital
London, E1 1FR, United Kingdom
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Salford Royal Hospital NHS Trust
Manchester, M6 8HD, United Kingdom
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Sheffield Teaching Hospitals NHS Foundation Trust
Sheffield, S10 2JF, United Kingdom
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St George's University Hospitals NHS Foundation Trust
London, SW17 0RE, United Kingdom
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University Hospital Hairmyres, NHS Lanarkshire
Glasgow, G75 8RG, United Kingdom
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University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital Birmingham
Birmingham, B15 2TH, United Kingdom
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University Hospitals Plymouth NHS Trust
Plymouth, PL6 8DH, United Kingdom
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University Hospitals of Coventry and Warwickshire NHS Trust
Coventry, CV2 2DX, United Kingdom
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University Hospitals of North Midlands NHS Trust
Stoke-on-Trent, ST4 6QG, United Kingdom
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Walton Centre NHS Trust
Liverpool, L9 7LJ, United Kingdom
Conditions
Explore the condition pages connected to this study.