Gene sleuths hunt down the true source of blood infections in hospitalized kids
NCT ID NCT02271243
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to figure out where bloodstream infections in children with central lines actually come from. By comparing the DNA of bacteria from the blood with bacteria from the gut, mouth, and skin, researchers hope to tell whether the infection started from the line itself or from damage to the gut or airway. The study will enroll 60 children at Boston Children's Hospital and use advanced genetic sequencing to trace the infection's origin.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors better understand whether a bloodstream infection comes from the central line or from gut or airway damage, leading to more accurate diagnosis and treatment.
- What could go wrong
- This is a small, early observational study (60 participants) at a single hospital, so results may not apply to all patients. It is not testing a treatment, so no direct benefit to participants.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Boston Children's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
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