Can a natural amino acid shorten sickle cell pain crises? new trial aims to find out
NCT ID NCT06635902
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a natural substance called citrulline, given through an IV, can help children and teens with sickle cell disease recover faster from severe pain episodes. About 99 hospitalized participants aged 4 to 21 will receive either citrulline or a placebo for 16 hours. Researchers will measure how long the pain lasts and how much pain medicine is needed, while also checking for side effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Children's National Hospital
RECRUITINGWashington D.C., District of Columbia, 20010, United States
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