Supercharged immune cells aim to beat back tough leukemia
NCT ID NCT02782546
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial tests whether giving patients with hard-to-treat acute myeloid leukemia (AML) a special type of immune cell—called a cytokine-induced memory-like natural killer (NK) cell—after a stem cell transplant can improve their chances of staying cancer-free. About 60 adults with AML that did not respond to standard treatments will receive a donor stem cell transplant followed by these memory-like NK cells. The goal is to see if this combination can boost leukemia-free survival at 100 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
memory-like natural killer (NK) cells
What this could lead to
If successful, this could offer a new treatment option for patients with hard-to-treat acute myeloid leukemia, potentially improving their chances of staying cancer-free.
What could go wrong
This is an early-phase trial with only 60 participants, so results may not apply to everyone. There are risks of graft failure, severe graft-versus-host disease, or the treatment not working as hoped.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Washington University School of Medicine
St Louis, Missouri, 63110, United States