Experimental drug cilengitide tested with Chemo-Radiation for lung cancer

NCT ID NCT01118676

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tested the drug cilengitide given continuously along with standard chemotherapy and radiation in 14 patients with locally advanced non-small cell lung cancer. The main goal was to find the highest safe dose of cilengitide when used this way. Researchers also looked at how well the tumors responded and how long patients lived.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
cilengitide
What this could lead to
If successful, this could help determine a safe dose of cilengitide combined with standard chemoradiation for advanced lung cancer.
What could go wrong
This is a very early, small Phase 1 trial with only 14 patients, so it cannot prove effectiveness. The main goal is safety, not treatment benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Toulouse Larrey

    Toulouse, 31000, France

  • Institut Claudius Regaud

    Toulouse, 31000, France

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