Experimental drug cilengitide tested with Chemo-Radiation for lung cancer

NCT ID NCT01118676

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tested the drug cilengitide given continuously along with standard chemotherapy and radiation in 14 patients with locally advanced non-small cell lung cancer. The main goal was to find the highest safe dose of cilengitide when used this way. Researchers also looked at how well the tumors responded and how long patients lived.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cilengitide

What this could lead to

If successful, this could help determine a safe dose of cilengitide combined with standard chemoradiation for advanced lung cancer.

What could go wrong

This is a very early, small Phase 1 trial with only 14 patients, so it cannot prove effectiveness. The main goal is safety, not treatment benefit.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU Toulouse Larrey

    Toulouse, 31000, France

  • Institut Claudius Regaud

    Toulouse, 31000, France