New hope for tough lymphoma: experimental drug CHO-H01 enters human trials

NCT ID NCT05950165

Recruiting now Disease control Sponsor: Cho Pharma Inc. Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests an experimental drug called CHO-H01, alone or with lenalidomide, in people with non-Hodgkin lymphoma that has returned or not responded to prior treatments. The trial has two parts: first, finding a safe dose of CHO-H01 alone; second, testing the combination in low-grade lymphoma. Up to 37 participants will be monitored for side effects and tumor response.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: CHO-H01 (an experimental drug) and lenalidomide
What this could lead to: If successful, this could offer a new treatment option for people with hard-to-treat non-Hodgkin lymphoma that has not responded to other therapies.
What could go wrong: This is an early-phase trial with only 37 participants, so results may not apply broadly. The drug may cause side effects or fail to shrink tumors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia B-cell non-Hodgkin lymphoma diffuse large B-cell lymphoma follicular lymphoma mantle cell lymphoma marginal zone lymphoma non-Hodgkin lymphoma primary mediastinal large B-cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-HODGKIN LYMPHOMA

Contacts and locations

Locations

Chang Gung Medical Foundation - Kaohsiung Chang Gung Memorial Hospital - Hemato-Oncology
RECRUITING

Kaohsiung City, 833, Taiwan
Chang Gung Medical Foundation - LinKou Chang Gung Memorial Hospital - Hematology and Oncology - Hematology and Oncology
TERMINATED

Taoyuan, Taoyuan, 33305, Taiwan
Chi-Mei Medical Center
RECRUITING

Tainan, Taiwan, 71004, Taiwan
China Medical University Hospital - Hematology/Oncology - Taichung
RECRUITING

Taichung, 404, Taiwan
National Cheng Kung University Hospital - Internal Medicine
TERMINATED

Tainan, 70403, Taiwan
National Taiwan University Hospital - Hematology And Oncology
RECRUITING

Taipei, 100, Taiwan
National Taiwan University Hospital Yunlin Branch
RECRUITING

Huwei, Taiwan, 632, Taiwan
Taipei Medical University - Shuang Ho Hospital - Oncology
RECRUITING

New Taipei City, Taipei Special Municipality, 23561, Taiwan
Tri-Service General Hospital - Neihu Branch - Hematology
TERMINATED

Taipei, Taipei, 11490, Taiwan

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