Could neck adjustments relieve Cancer-Related fatigue?

NCT ID NCT06235671

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled This study
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 27, 2026 · Last updated Aug 28, 2026 · Updated 1 time

Summary

This trial tests whether six weeks of upper cervical chiropractic care can help adults who have finished cancer treatment but still struggle with chronic fatigue. The study focuses on whether such a trial is practical, looking at recruitment, adherence, and acceptability. Participants are cancer survivors aged 18 to 65 with no active disease. The results will guide a future, larger study on chiropractic care for cancer-related fatigue.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Upper cervical chiropractic care, a procedure involving 6 weeks of chiropractic sessions
What this could lead to
If this trial succeeds, it could point toward a non-drug way to ease chronic fatigue in cancer survivors, and support a larger study to confirm the benefit.
What could go wrong
This is a small feasibility trial, not a proof of effectiveness. It may not show clear benefits, and chiropractic care carries rare risks like injury from neck manipulation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Expected to start

Oct 2024

An estimate. Start dates often move.

Expected to finish

May 2025

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Able to understand and provide written informed consent in English * 18-65 years of age * Informed by primary health care provider that there is no evidence of active disease (this is sometimes referred to as "complete remission" or "cured") * Minimum of 3 months since completion of primary curative-intent cancer therapies including surgery, chemotherapy, radiotherapy, and/or immunotherapy (long-term hormonal therapy permitted) * Onset of fatigue occurred at some point during illness and/or treatment * FACIT-Fatigue scale score in the moderate-to-severe range (i.e., at or above the 60th percentile) * If on any prescription medication (including hormonal therapy), on a stable dose for a minimum of 12 weeks with no plans to change medications or doses during the study Exclusion Criteria: * Taking any short-acting benzodiazepine including midazolam \& triazolam * Known disorder resulting in syncope/fainting during postural changes (e.g., postural orthostatic tachycardia syndrome, orthostatic hypotension) * Pacemaker or known heart condition that influences the electrical or mechanical function of the heart (e.g., severe heart valve disease) * Diagnosed with an externalizing (e.g., substance use, antisocial disorder) or thought (e.g., schizophrenia, paranoid personality, bipolar) disorder that is uncontrolled or untreated * Diagnosed with rheumatoid arthritis, osteoporosis, or cervical spine instability * Currently pregnant * Current litigation related to a physical, health-related injury * Chronic pain rated at least 3/10 on a visual analog scale (VAS)

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dr. Sid E. Williams Center for Chiropractic Research

    Atlanta, Georgia, 30308, United States

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