New hope for kids with rare, severe arthritis in global drug trial

NCT ID NCT05609630

Summary

This study is testing how well and how safe the drug upadacitinib is for children and teenagers (ages 1 to under 18) with a rare and serious form of childhood arthritis called systemic juvenile idiopathic arthritis (sJIA). It will compare upadacitinib to another existing treatment, tocilizumab. About 90 children worldwide will take one of the medications for about a year to see if it reduces joint pain, swelling, fever, and other disease symptoms.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Asklepios Klinik Sankt Augustin /ID# 251565

    RECRUITING

    Sankt Augustin, North Rhine-Westphalia, 53757, Germany

  • Azienda Ospedaliero Universitaria Meyer /ID# 251775

    RECRUITING

    Florence, Firenze, 50139, Italy

  • CMiP - Centro Mineiro de Pesquisa Ltda - ME /ID# 251769

    COMPLETED

    Juiz de Fora, Minas Gerais, 36010-570, Brazil

  • CREA de Guadalajara SC /ID# 252917

    RECRUITING

    Guadalajara, Jalisco, 44620, Mexico

  • Centro de Investigaciones Medicas Tucuman /ID# 251781

    RECRUITING

    San Miguel de Tucumán, Tucumán Province, 4000, Argentina

  • Children'S Hospital Of Soochow University /ID# 251755

    RECRUITING

    Suzhou, Jiangsu, 215025, China

  • Children's Hospital of Fudan University /ID# 251619

    RECRUITING

    Shanghai, Shanghai Municipality, 200032, China

  • Childrens National Medical Center /ID# 253344

    RECRUITING

    Washington D.C., District of Columbia, 20010-2916, United States

  • Cincinnati Childrens Hospital Medical Center /ID# 251827

    RECRUITING

    Cincinnati, Ohio, 45229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Gazi University Medical Faculty /ID# 253677

    RECRUITING

    Ankara, 06560, Turkey (Türkiye)

  • Great Ormond Street Children's Hospital /ID# 251512

    RECRUITING

    London, Greater London, WC1N 3HZ, United Kingdom

  • Hamburger Zentrum fuer Kinder- und Jugendrheumatologie /ID# 251564

    RECRUITING

    Hamburg, 22081, Germany

  • Hospital Sant Joan de Deu /ID# 251353

    RECRUITING

    Esplugues de Llobregat, Barcelona, 08950, Spain

  • Hospital Sao Paulo /ID# 251765

    RECRUITING

    São Paulo, 04023-062, Brazil

  • Hospital Universitario y Politecnico La Fe /ID# 251352

    RECRUITING

    Valencia, 46026, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao /ID# 251764

    RECRUITING

    São Paulo, 05403-000, Brazil

  • Hospital de Niños de la Santisima Trinidad /ID# 252736

    RECRUITING

    Córdoba, 5014, Argentina

    Contact Phone: •••-•••-••••

  • Hyogo Prefectural Kobe Children'S Hospital - Minatojima /ID# 251649

    RECRUITING

    Kobe, Hyōgo, 650-0045, Japan

    Contact Phone: •••-•••-••••

  • IRCCS Istituto Giannina Gaslini /ID# 251776

    RECRUITING

    Genoa, Genova, 16147, Italy

  • Institute of Science Tokyo Hospital /ID# 251505

    RECRUITING

    Bunkyo-ku, Tokyo, 113-8519, Japan

  • Instituto CAICI S.R.L /ID# 251448

    RECRUITING

    Rosario, Santa Fe Province, 2000, Argentina

  • Istanbul Universitesi-Cerrahpasa Cerrahpasa Tip Fakultesi /ID# 251651

    RECRUITING

    Istanbul, 34098, Turkey (Türkiye)

  • Istanbul University Istanbul Medical Faculty /ID# 251652

    RECRUITING

    Istanbul, 34093, Turkey (Türkiye)

  • Landeskrankenhaus Bregenz /ID# 266317

    RECRUITING

    Bregenz, Vorarlberg, 6900, Austria

  • Levine Children's Hospital /ID# 253491

    RECRUITING

    Charlotte, North Carolina, 28203, United States

  • Linkou Chang Gung Memorial Hospital /ID# 267390

    RECRUITING

    Taoyuan, 333, Taiwan

  • Monash Health - Monash Medical Centre /ID# 251691

    COMPLETED

    Clayton, Victoria, 3168, Australia

  • National Taiwan University Hospital /ID# 267387

    RECRUITING

    Taipei, 100, Taiwan

  • New York Medical College /ID# 253437

    RECRUITING

    Valhalla, New York, 10595, United States

    Contact Phone: •••-•••-••••

  • Niigata University Medical & Dental Hospital /ID# 251538

    RECRUITING

    Niigata, Niigata, 951-8520, Japan

  • Osaka Medical and Pharmaceutical University Hospital /ID# 252092

    RECRUITING

    Takatsuki-shi, Osaka, 569-8686, Japan

  • Phoenix Children's Hospital /ID# 253403

    RECRUITING

    Phoenix, Arizona, 85016-7710, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Queen Silvia Children's Hosp /ID# 251318

    RECRUITING

    Gothenburg, Västra Götaland County, 416 85, Sweden

    Contact Phone: •••-•••-••••

  • Randall Children's Hospital /ID# 251829

    RECRUITING

    Portland, Oregon, 97227-1654, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Royal Children's Hospital /ID# 251663

    COMPLETED

    Parkville, Victoria, 3052, Australia

  • Semmelweis Egyetem /ID# 266750

    RECRUITING

    Budapest, 1085, Hungary

  • St Marianna University School Of Medicine /ID# 251623

    RECRUITING

    Kawasaki-shi, Kanagawa, 216-8511, Japan

  • St. Josef-Stift Sendenhorst /ID# 268680

    RECRUITING

    Sendenhorst, North Rhine-Westphalia, 48324, Germany

  • The Children's Hospital of Zhejiang University School of Medicine /ID# 251754

    RECRUITING

    Hangzhou, Zhejiang, 310003, China

  • The Childrens Hospital of Chongqing Medical University /ID# 251539

    RECRUITING

    Chongqing, Chongqing Municipality, 400065, China

  • Umraniye Training and Res Hosp /ID# 251653

    RECRUITING

    Istanbul, 34764, Turkey (Türkiye)

  • Universitaetsklinikum Freiburg /ID# 253288

    RECRUITING

    Freiburg im Breisgau, Baden-Wurttemberg, 79106, Germany

    Contact Email: •••••@•••••

  • Universitair Medisch Centrum Utrecht /ID# 267435

    RECRUITING

    Utrecht, 3584 CX, Netherlands

  • Xi'an Children's Hospital /ID# 251693

    RECRUITING

    Xi'an, Shaanxi, 710054, China

Conditions

Explore the condition pages connected to this study.