New combo therapy aims to stop lung cancer return after surgery
NCT ID NCT04564157
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase III trial tests whether adding immunotherapy to standard chemotherapy after lung cancer surgery can delay or prevent the cancer from coming back. It enrolls 210 patients with stage IB-IIIA non-small cell lung cancer that was completely removed. Participants are randomly assigned to receive either chemotherapy alone or chemotherapy followed by maintenance immunotherapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Carboplatin and Paclitaxel (chemotherapy) plus immunotherapy
What this could lead to
If successful, this could show that adding immunotherapy after surgery and chemotherapy helps keep lung cancer from coming back longer than chemotherapy alone.
What could go wrong
This is a Phase III trial, but results are not yet available. Adding immunotherapy may increase side effects without guaranteeing better outcomes.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Complejo Hospitalario de Navarra
Pamplona, Pamplona, 31008, Spain
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Complexo Hospitalario Universitario De Vigo
Vigo, Vigo, 36204, Spain
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Hospital Clínico San Carlos
Madrid, Madrid, 28040, Spain
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Hospital Clínico de Valencia
Valencia, Valencia, 46010, Spain
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Hospital Fundación de Alcorcón
Madrid, Madrid, 28922, Spain
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Hospital General Universitario de Alicante
Alicante, Alicante, 03010, Spain
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Hospital General Universitario de Valencia
Valencia, Valencia, 46014, Spain
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Hospital Parc Taulí
Barcelona, Barcelona, 08208, Spain
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Hospital Puerta de Hierro
Madrid, Madrid, 28222, Spain
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Hospital San Pedro De Alcántara
Cáceres, Cáceres, 10003, Spain
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Hospital Son Espases
Palma de Mallorca, Palma de Mallorca, 07120, Spain
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Hospital Universitari Quiron Dexeus
Barcelona, Barcelona, 08028, Spain
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Hospital Universitari Vall d' Hebron
Barcelona, Barcelona, 08035, Spain
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Hospital Universitario Cruces
Barakaldo, Vizcaya, 48903, Spain
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Hospital Universitario Fundación Jiménez Díaz
Madrid, Madrid, 28040, Spain
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Hospital Universitario Insular de Gran canaria
Las Palmas de Gran Canaria, Gran Canaria, 35016, Spain
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Hospital Universitario La Fe
Valencia, Valencia, 46026, Spain
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Hospital Universitario Lucus Augusti
Lugo, Lugo, 27003, Spain
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Hospital Universitario Nuestra Señora La Candelaria
Santa Cruz de Tenerife, Santa Cruz de Tenerife, 38009, Spain
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Hospital Universitario Virgen de la Arrixaca
El Palmar, El Palmar, 30120, Spain
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Hospital Universitario de Jaén
Jaén, Jaén, 23007, Spain
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Hospital Universitario la Paz
Madrid, Madrid, 28046, Spain
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Hospital Virgen del Rocío
Seville, Sevilla, 41013, Spain
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Hospital de Basurto
Bilbao, Bilbao, 48013, Spain
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Hospital de la Santa Creu i Sant Pau
Barcelona, Barcelona, 08041, Spain
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Hospitalario Universitario A Coruña
A Coruña, La Coruña, 15006, Spain
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ICO Badalona, Hospital Germans Trias i Pujol
Badalona, Barcelona, 08916, Spain
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ICO Girona, Hospital Josep Trueta
Girona, Girona, 17007, Spain
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ICO Hospitalet
L'Hospitalet de Llobregat, Barcelona, 08908, Spain
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Instituto Valenciano De Oncología
Valencia, Valencia, 46009, Spain