Could chemo after surgery beat endometrial cancer relapse?
NCT ID NCT01244789
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether giving chemotherapy after surgery can help people with early-stage (stage I-II) endometrial cancer who have a higher risk of the cancer coming back. About 244 patients will either receive six cycles of carboplatin and paclitaxel or simply be observed. The goal is to see if chemo improves overall survival compared to observation alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- carboplatin and paclitaxel (chemotherapy)
- What this could lead to
- If successful, this could show that chemotherapy after surgery helps more people with early-stage endometrial cancer live longer without the disease coming back.
- What could go wrong
- This is a phase 2 trial, so results are still uncertain. Chemotherapy can cause side effects like fatigue, nausea, and nerve damage, and it may not improve survival for all patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Danish Gynecological Cancer Group (DGCG)
Copenhagen, 2100, Denmark
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