Chemo's muscle impact under the microscope in small breast cancer study
NCT ID NCT06536556
First seen Jan 11, 2026 · Last updated Jun 23, 2026 · Updated 25 times
Summary
This study looked at how a single round of chemotherapy affects the muscles of women with early-stage breast cancer. Researchers compared three common chemo regimens: paclitaxel alone, paclitaxel plus trastuzumab, and paclitaxel plus carboplatin. They took muscle biopsies and measured strength, body composition, and quality of life before and four days after treatment. The study was terminated early and only enrolled 5 participants, so the findings are very limited.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for BREAST CANCER are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Institut de cancérologie Strasbourg europe
Strasbourg, 67033, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
paclitaxel, trastuzumab, carboplatin
What this could lead to
If successful, this could help doctors understand how chemotherapy affects muscle health in breast cancer patients, potentially leading to better supportive care.
What could go wrong
The study was terminated early with only 5 participants, so results are very limited and may not be reliable. It was designed to observe short-term changes, not to test a new treatment.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.