Could a common heart drug boost cancer treatment?

NCT ID NCT05651594

First seen Jan 04, 2026 · Last updated Jun 12, 2026 · Updated 28 times

Summary

This study tests whether adding propranolol (a beta-blocker used for heart conditions) to standard chemotherapy and immunotherapy can help shrink tumors in people with advanced esophageal or gastroesophageal junction cancer that cannot be surgically removed. The trial enrolls 40 adults who have not received prior treatment for their advanced cancer. Researchers believe propranolol may reduce stress-related hormones that can weaken the immune system, potentially making the other treatments more effective.

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Contacts and locations

Locations

  • Roswell Park Cancer Institute

    RECRUITING

    Buffalo, New York, 14263, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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Conditions

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