CLINICAL STAGE IV ESOPHAGEAL ADENOCARCINOMA AJCC V8
Clinical trials for CLINICAL STAGE IV ESOPHAGEAL ADENOCARCINOMA AJCC V8 explained in plain language.
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Major cancer trial tests if adding one drug helps patients live longer
Disease control Recruiting nowThis large, late-stage trial is testing which of two chemotherapy combinations works better for people with advanced stomach or esophageal cancer that has spread and cannot be removed by surgery. About 382 participants will be randomly assigned to receive either the standard two-…
Matched conditions: CLINICAL STAGE IV ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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New hope for Tough-to-Treat cancers: adding immune booster to standard care
Disease control Recruiting nowThis study is for people with advanced stomach or esophageal cancer that has worsened after initial treatment. It tests if adding an immunotherapy drug called nivolumab to the standard two-drug chemotherapy helps control the cancer better and helps patients live longer. About 224…
Matched conditions: CLINICAL STAGE IV ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: PHASE2, PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Stress-Blocking pill joins fight against tough stomach cancers
Disease control Recruiting nowThis study is testing if adding propranolol, a common blood pressure and anxiety medication, makes standard chemotherapy and immunotherapy more effective for people with advanced cancer where the esophagus meets the stomach. The idea is that stress hormones might weaken the immun…
Matched conditions: CLINICAL STAGE IV ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Can a simple ear tap fight cancer weight loss?
Symptom relief Recruiting nowThis study is testing if a simple, non-invasive therapy called ear acupressure can help improve appetite and prevent weight loss in people with certain advanced cancers. Researchers will recruit 66 patients with stomach, esophageal, or pancreatic cancer to see if applying small a…
Matched conditions: CLINICAL STAGE IV ESOPHAGEAL ADENOCARCINOMA AJCC V8
Phase: NA • Sponsor: University of Washington • Aim: Symptom relief
Last updated Mar 12, 2026 13:52 UTC
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Scientists build a living library of cancer to unlock treatment secrets
Knowledge-focused Recruiting nowThis study is collecting tissue and blood samples from cancer patients over time to create a research resource called a biobank. Researchers will analyze these samples to understand how cancer changes during treatment and why some treatments stop working. The goal is to help scie…
Matched conditions: CLINICAL STAGE IV ESOPHAGEAL ADENOCARCINOMA AJCC V8
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Mar 17, 2026 13:09 UTC