Chemo-brain mystery: study dives into thinking changes in older breast cancer patients

NCT ID NCT02290834

First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 2 times

Summary

This study looks at how chemotherapy affects thinking and the brain in older adults (age 60+) with breast cancer. Researchers will track changes in memory and thinking skills, and use brain scans to see if certain proteins are linked to these changes. The goal is to better understand 'chemo-brain' and who might be most at risk.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm Chemotherapy-Related Cognitive Impairment Cognition Disorders cognitive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • Massachusetts General Hospital/North Shore Cancer Center

    RECRUITING

    Salem, Massachusetts, 01970, United States

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